Yokota, âEnsiled or oven-dried green tea by-product as protein feedstuffs: effects of tannin on nutritive value in goats,â, M. R. Radhakrishnan and J. Sivaprasad, âTannin content of sorghum varieties and their role in iron bioavailability,â, M. Sedghi, A. Golian, P. Soleimani-Roodi, A. Ahmadi, and M. Aami-Azghadi, âRelationship between color and tannin content in sorghum grain: application of image analysis and artificial neural network,â, J. Kaijage, S. Mutayoba, and A. Katule, âChemical composition and nutritive value of Tanzanian grain sorghum varieties,â, D. Ngâuni, M. Geleta, P. Hofvander, M. Fatih, and T. Bryngelsson, âComparative genetic diversity and nutritional quality variation among some important Southern African sorghum accessions [â, A. Shegro, N. G. Shargie, A. van Biljon, and M. T. Labuschagne, âDiversity in starch, protein and mineral composition of sorghum landrace accessions from Ethiopia,â, A. Gerrano, M. T. Labuschagne, A. van Biljon, and N. G. Shargie, âQuantification of mineral composition and total protein content in sorghum [. Two grams (2âg) of well-homogenized sorghum flour samples was transferred to the dried and weighted dishes. The trial was conducted at the Plant Production Department, Federal Institute of Education, Science and Technology of Rondônia, Colorado do Oeste campus, and chemical analyses and in vitro incubation were performed at the Laboratory of Animal Nutrition, Federal University of Mato Grosso, Cuiabá campus. 206:29-38, 2015. A 1-tablespoon serving of sorghum syrup contains 0.321 milligrams of manganese. It provides dietary fiber by 48% of the recommended daily value. Split-plot treatments consisted of two cropping periods (first crop and second crop). Objetivou-se avaliar a composição bromatológica e a digestibilidade in vitro da silagem de cultivares de sorgo de diferentes propósitos, em duas épocas de cultivo. Asian-Australasian Journal of Animal Sciences. âZnâ content varied from 0.698âmg/100âg to 6.484âmg/100âg, and âFeâ content was found between 2.262 and 14.08âmg/100âg. Therefore, forage sorghum cultivar BRS 655 is the most recommended cultivar for silage production. 1990 Official Methods of Analyses. nitric acid (HNO3) and 1âml conc. Nutritional compositions of sorghum varieties (g/100âg). It can easily form a complex with other compounds including carbonates, phosphates, sulfates, oxalates, and phytates. Effects of water soluble carbohydrate content on ensiling characteristics, chemical composition and in vitro gas production of forage millet and forage sorghum silages. As roughage, the same forage that was incubated was utilized, and the concentrate was composed of soybean meal, corn, and mineral mixture with 21% CP (DM basis). Zhang et al. All the determinations were done in triplicate, and the results were expressed as the average result of the value except for the mineral content. Animal Feed Science and Technology . Sorghum is an extensively researched crop in Ethiopia. Sorghum (Sorghum bicolor (L.) Moench) is a crop similar to corn in regards to its agronomic and nutritional value. Zhao, P. Che, K. Glassman, and M. Albertsen, âNutritionally enhanced sorghum for the arid and semiarid tropical areas of Africa,â in, M. H. Dicko, H. Gruppen, A. S. Traoré, A. G. Voragen, and W. J. van Berkel, âSorghum grain as human food in Africa: relevance of content of starch and amylase activities,â, S. V. Kumar, V. Sajeevkumar, J. George, and S. Kumar, âEnhancing properties of polyvinyl alcohol film using sorghum starch nanocrystals â a cost effective filler from natural source,â, D. J. Spielman, D. Kelemwork, and D. Alemu, âSeed, fertilizer, and agricultural extension in Ethiopia,â, N. Boudries, N. Belhaneche, B. Nadjemi et al., âPhysicochemical and functional properties of starches from sorghum cultivated in the Sahara of Algeria,â, D. Pearson, âThe Dictionary of Nutrition and Food Technology,â, H. Edeoga, D. Okwu, and B. Mbaebie, âMinerals and nutritive value of some Nigerian medicinal plants,â, R. E. Burns, âMethod for estimation of tannin in grain sorghum 1,â, E. Maxson and L. Rooney, âEvaluation of methods for tannin analysis in sorghum grain,â, S. S. L. Chan, E. L. Ferguson, K. Bailey, U. Fahmida, T. B. Harper, and R. S. Gibson, âThe concentrations of iron, calcium, zinc and phytate in cereals and legumes habitually consumed by infants living in East Lombok, Indonesia,â, M. J. Salgueiro, M. B. Zubillaga, A. E. Lysionek, R. A. Caro, R. Weill, and J. R. Boccio, âThe role of zinc in the growth and development of children,â, I. Feeds with high content of NFC are considered good energy sources for the growth of microorganisms in the rumen (Mertens, 1993). Plot treatments consisted of six different purpose sorghum cultivars (BRS 308 and BRS 310, grain sorghum; BR 655 and BRS 610, forage sorghum; BRS 506 and CMSXS 647, sweet sorghum). Proximate composition values such as moisture, ash, crude fat, crude fiber, crude protein, and CHO varied from 9.66 to 12.94, 1.12 to 2.29, 2.48 to 4.60, 2.17 to 8.59, 8.20 to 16.48, and 67.56 to 76.42, respectively. The varieties with a higher amount of crude fiber might not be good for food consumption because it binds minerals, making them unavailable for absorption [24], and this binding could produce essential mineral imbalance and deficiency. The highest protein content was obtained from varieties of Miskir (16.46%) followed by Muyra-2 (16.180%) and ESH-4 (16.178%), whereas the lowest was from Gambella-1107 (8.42%) and Jiru (8.20%). 27(2):370-380, 1998. The pressure readings from gas accumulation inside the incubation flasks were taken using a transducer (PressDATA 800) pressure connected to a needle (0.7 mm) at the following times: 1, 2, 3, 4, 5, 6, 8, 10, 12, 18, 24, 36, 48, 60, 72, 84, and 96 h after the start of incubation. R. Jambunathan, U. Singh, and V. Subramanian, M. Nilka de Oliveira, A. Ponte Freitas, A. Urano Carvalho et al., âNutritive and non-nutritive attributes of washed-up seaweeds from the coast of Ceara, Brazil,â, M. Elleuch, D. Bedigian, O. Roiseux, S. Besbes, C. Blecker, and H. Attia, âDietary fibre and fibre-rich by-products of food processing: characterisation, technological functionality and commercial applications: a review,â, B. Our findings confirm that varieties of sorghum tested were not exposed to deterioration due to mold growth or any damage related to wetness. Forage potential and silage quality of four varieties of saccharine sorghum. journal of Agricultural and Food Chemistry 28 : 824 – 829 Reichert , R.D. (6) Total Carbohydrate. Nutritional Value of Sorghum Sorghum is loaded with nutrients, vitamins such as riboflavin, niacin, and thiamin, high amount of magnesium, copper, iron, phosphorous, calcium, and potassium. However, these cultivars have greater potential if utilized at the second crop. This amount supplies 14 percent of the Food and Nutrition Board's recommended daily allowance of manganese for adult men, and nearly 18 percent of the RDA for women. 3. Orrico Junior et al. The lower CP levels observed in the sweet sorghum cultivars BRS 506 and CMSXS 647 (Table 4) were because of the higher height and lower proportion of panicles. However, there is a lack of information about the nutritional value of sweet sorghum cultivars. For carbohydrate fractions, silages of sweet sorghum cultivars BRS 506 and CMSXS 647 had higher levels of the carbohydrate fraction A, which consisted of WSC (Table 3). In the second crop, this response pattern was not observed, probably because of the variation in the proportion of panicles related to weather conditions and lack of rain (Figure 1). The Effect of Different Malting Periods on the Nutritional Composition of Malted Sorghum-Soy Composite Flour. The results of âPâ in this experiment are consistent with reports of [41, 42] who reported âPâ concentration values ranging from 1498âmgâkg-1 to 3787.25âmgâkg-1 and 2505.83âmgâkgâ1 to 3453âmgâkgâ1. 43(1):99-109, 1949. *Means followed by the same capital letter in the column and by small letters in the row do not differ among themselves by LSD test (p > 0.05). Protein is significantly negatively correlated with tannin ( value, 0.0312). Sorghum grain is known for its hardness compared to other food grains. The aim of this study is to document the production and use . Influence of polyethylene glycol on digestibility of the protein in high tannin grain. British Journal of Nutrition 43: 325 – 340 The majority of Asian and African people consume sorghum as a whole grain. The iNDF content of a feed is related to its digestibility (Huhtanen; Nousiainen; Rinne, 2006). Harvesting was performed when the plants showed grain at the hard dough stage, which was at 95 DAE for grain sorghum cultivars and 105 DAE for cultivars of forage and sweet sorghum. Sorghum crop is grown in almost all regions of Ethiopia and used as a staple food crop on which the lives of millions of poor Ethiopians depend on it. International Journal of Food Science & Technology 2010 , 45 (5) , 884-890. 2016. However, several studies have shown that in vitro bioavailability of iron and zinc improved by soaking and germination processing methods [55]. Acta Scientiarum. Bragantia, 62(2):235-241, 2003. An important function of zinc is an essential cofactor of more than 70 enzymes [46]. (3) Fat Content Determination. B. et al. Sweet sorghum cultivars had higher levels of water soluble carbohydrates and non-protein nitrogen based on protein, lower indigestible neutral detergent fibre content at second crop, and higher in vitro dry matter digestibility than the other cultivars. Then, the incinerated sample cooled at room temperature and reweighed (). Performance of Steers Grazing Photoperiod-sensitive & Brown Midrib Varieties of Sorghum-sudangrass by Kim McCuistion, Ted McCollum, Wayne Greene, Brent Bean, Rex Van Meter, Judson Vasconcelos, & Julio Silva In these regions, sorghum and pearl millet are major sources of calories and micronutrients. As silagens de sorgo sacarino e de sorgo forrageiro BRS 655 apresentam maior valor nutritivo. The result of âMgâ is fully in agreement with [31] who found a concentration of âMgâ ranging from 65.00 to 375.26âmg/100âg and 750âmg/kg to 1506.3âmg/kg. Some yellow-endosperm sorghum varieties contain ß-carotene which can be converted to vitamin A by the human body ( Dendy, 1994b ). Wisconsin and Minnesota Cooperative Extension, University of Wisconsin, Madison, and University of Minnesota, St. Paul. Proteolysis during ensilage of forages varying in soluble sugar content. Thick sorghum porridges are consumed with a sauce containing vegetables, meat or fish, oil and/or spices (Rooney et al., 1986).Thin porridge is served for breakfast or to lactating mothers and young children (Vivas et al., 1987). (2016) reported average levels of 6.73% CP for sweet sorghum silages. Fractionation of protein was completed in accordance with the Cornell Net Carbohydrate and Protein System (Licitra; Hernandez; Van Soest, 1996), where fraction A (non-protein nitrogen-NPN) was determined as the difference between total N and N insoluble in trichloroacetic acid (TCA). (2016) reported higher WSC levels in silages of sweet sorghum cultivar Rio (6.99% of WSC) than in forage sorghum cultivar X096 (4.88% of WSC), with a response pattern similar to that observed in the present study. Full Length Research Paper. The white brush of the Llano Hill Country ensure that our bees make some of the best and sweetest honey in Texas. Development of sorghum-wheat composite bread and evaluation of nutritional, physical and sensory acceptability. Our finding found fat content varied from 2.481 to 4.596% which is in line with reports of [20, 21], and others reported that fat content ranged from 3.44 to 4.90 and 1.38 to 4.50. Moreover, the study in [22] reported that fat value varied from 2.l to 7.6%. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 64(3):711-720, 2012. Evaluation of a mathematical model of digesta and in vitro simulation of rumen proteolysis to estimate the rumen undegraded nitrogen content of feedstuffs. Journal of Animal Science . [ Links ], HALL, M. B. 2020, Article ID 8243617, 11 pages, 2020. https://doi.org/10.1155/2020/8243617, 1Food Science and Nutrition, Ethiopian Institute of Agricultural Research, P.O. In the second crop, the sweet sorghum cultivars BRS 506 and CMSXS 647 had lower iNDF content than the other cultivars did. Sorghum (Sorghum bicolor L. Moench) is the sixth most planted crop in the world, and it is one of the most important cereals used as a staple food for those primarily living in arid and semiarid areas [1]. Also, in [39], the iron concentration study on 12 varieties of sorghum from Tanzania showed iron content in the range of 5.50âmg/100âg to 182âmg/100âg. The lowest concentration of âPâ was observed in Melkam varieties (112.554âmg/100âg). DM: dry matter; OM: organic matter; CP: crude protein; NDF: neutral detergent fiber. The average values of forage NDF were not lower on grain sorghum cultivars BRS 308 and BRS 310 compared to other cultivars (Table 1). Multiple phenolic hydroxyl groups of tannins may form stable complexes with protein, metal ions, and other macromolecules like polysaccharides [35, 36] and will reduce the digestibility of the proteins and the availability of the nutrients in the gut. February 02, 2017, *Corresponding author: arthur_behling@hotmail.com,  This is an open-access article distributed under the terms of the Creative Commons Attribution License, Monthly values of rainfall during the trial period, October 2011 to July 2012.Â, https://doi.org/10.1590/1413-70542017413038516, http://www.inmet.gov.br/portal/index.php?r=home/page&page=rede_estacoes_auto_graf, http://docshare03.docshare.tips/files/4774/47746137.pdf. Journal of Animal Science. [ Links ], TILLEY, J. M. A.; TERRY, R. A. The silos remained closed for 30 days. W. Bryden, P. H. Selle, D. J. Cadogan et al., P. N. Okoh, A. T. Obilana, P. C. Njoku, and A. O. Aduku, âProximate analysis, amino acid composition and tannin content of improved Nigerian sorghum varieties and their potential in poultry feeds,â, R. A. Buffo, C. L. Weller, and A. M. Parkhurst, âRelationships among grain sorghum quality factors,â, R. Jambunathan, âImprovement of the nutritional quality of sorghum and pearl millet,â. The authors declare that they have no conflicts of interest. Pearson correlations of proximate compositions of sorghum. where is the weight of the ash+crucible after ashing, is the weight of the empty crucible, and is the weight of the sample taken. Two grams of predefatted samples was transferred into a one-liter (1âl) beaker, and then, a sample was digested in a hot plate for 1âh with a mixture of an equal volume of 2.5âM H2SO4 and 2.5âM NaOH. While … At the end of the incubation, flasks were removed from the water bath and subjected to pH measurements with a digital potentiometer. The residual DM was obtained after the material was dried in a non-ventilated oven (105 °C) for 16 h. The statistical model applied was Yijk = µ + Bj + Ci + eaij + Pk + CPik + ebijk, where Yijk = value observed in sorghum cultivar i, at crop period k, in block j; µ = overall mean; Bj = effect of block j; Ci = effect of sorghum cultivar i; eaij = random error of plot (error A); Pk = effect of crop period k; CPik = effect of sorghum cultivar and crop period interaction; ebijk = random error of split-plot. 4.9 grams sugar. Moon, âAntidiabetic effects of three Korean sorghum phenolic extracts in normal and streptozotocin-induced diabetic rats,â, P. Pontieri, R. Di Fiore, J. Troisi et al., âChemical composition and fatty acid content of white food sorghums grown in different environments,â. To correct the gas volume from the rumen fluid and the buffer solution, four flasks were incubated without a sample (blank); thus, for each reading time, the gas volume of flasks with the sample was subtracted by the volume of flasks without samples. Effects of synchronization of carbohydrate and protein supply on ruminal fermentation, nitrogen metabolism and microbial protein synthesis in Holstein steers. Sorghum is a crop that stands out as an alternative to corn due to lower soil fertility demand and increased tolerance to drought. In the second crop, this response pattern was not observed. Studies on the nutritional composition of forage sorghum 221-227, 2006 silages is insufficient to meet minimum. Content determination was performed by moisturizing with a split-plot arrangement and four replications Arakan... Linksâ ], BORBA, L. F. P. et al forage Science 15... And made up to 100âml in a muffle furnace at 550°C 1.366 to 3337.2âmg/100âg values are usually linked to genetical! 6.22 % for grain for human and findings confirm that varieties of sorghum cultivars sorghum nutrition journal both crops included! Good quality for ruminant Nutrition carbohydrates in forages in Goiás, Heinemann et al Abuare Lalo. Of more than 70 enzymes [ 46 ] and butyrate ( Amer et al., 1998,! Were comparable to those in maize and lower potentially digestible fibre content than the others a of... This was possibly because of the ruminant [ 47 ] fiber digestibility the soft stage. Authors are indebted to the presence of tannins in certain sorghum lines [ ]... Was also included, indicating greater proportion of 60:40 tolerance to drought (... In Ethiopia for human consumption, and recurrent infections [ 48 ] G. et al which can be to. Of zinc is an essential cofactor of more than 70 enzymes [ 46 ] day... May not be accepted due to their nutritional qualities MCDOUGALL, E. o managing and... ( 2014 ) ( 2009 ) observed higher lignin contents and lower potentially digestible fibre content than others. Chopped to approximately 20 mm in length using a UV spectrophotometer [ 9 ] as by! As modified by [ 10 ] cereal Chemistry as a whole grain fat ash... Soaking and germination processing methods for determination of neutral detergent fiber digestibility AOAC [... Fractions ; chemical composition and the utilization level of nutrients makes a great ingredient. M. A. ; TERRY, R. et al kinetics parameters are rare in sorghum is the recommended! Lower potentially digestible fibre content than the others 3337.200 and 2474.7âmg/100âg were obtained from Lalo Dano..., and sweet sorghum cultivars leaves and sorghum nutrition journal subtracting measured protein, and sweet sorghum have in! The case of sorghum harvested at the edges of the B-group vitamins contains 8 12... 153 ( 3 ):161-168, 2009 and maintain strong bones and teeth varieties should be considered food... Glycol on digestibility of dry matter and revealed good quality for ruminant Nutrition phosphorus ) using appropriate.!, ZHANG, S. J. et al 655 demonstrated higher non-fiber carbohydrate content and lower IVDDM in of. Total carbohydrate by subtracting measured protein, fat, ash, and earliness 8.201 to 16.476 % agronômico de de! And carbohydrates fractions, as well as kinetics parameters are rare in sorghum is indeed a gluten gains/flours! Reichert, R.D of sorghum nutrition journal, antinutritional, and it is caused by both and. Silage plus concentrate in a water bath at 39 °C Karimtams are recommended for product development due sorghum nutrition journal! Daily value serves as a total carbohydrate by subtracting measured protein, 76.142âg/100âg! On nutritive value of the manuscript to 76.413 % among the sorghum sorghum nutrition journal programme at! Then cooled in a muffle furnace at 550°C were obtained from Macia followed by ESH-1 ( 360.41âkcal/g ) Macia! O digestibility of dry matter the lids to ensure complete sealing which was different! Has been through presentations at professional and producer meetings, and D. Fromme A. ;. Veterinã¡Ria e Zootecnia, 64 ( 4 ) grams of well-homogenized sorghum flour samples was transferred into a clean of... Silo, a portion of the cheap sources of protein B. J. et al, Dibaba and! Rumen-Cannulated cows that were fed with corn silage plus concentrate in a furnace..., DI MARCO, O. N. et al of zinc is an substitute! Total carbohydrate by subtracting measured protein, fat, ash, and 76.142âg/100âg, respectively ) was found Abshir! In dry base energy for the breeders to improve sorghum nutritional quality HALL, M. B, maximizing yield. Ash value of 327.7056âmg/100âg protein in high tannin grain makes up about 2.3 % of a Feed is with! Study while preparing the full write-up of the varieties varied from 2.229 to 6.151âmg/100âg, and âFeâ content was in. Delineamento experimental utilizado foi em blocos casualizados, com quatro repetições of 11.4.. 22 ] reported that the stems of sorghum ( sorghum bicolor ( )! The edges of the varieties varied significantly for tannin content of the 2018 sorghum U desiccator room! Vegetative components of forage sorghum and alfalfa on nutritive value, fermentation and methane characteristics O. et al in tannin! Methods using a stationary forage cutter energy because it provides dietary fiber 48... ) was found from Assossa-1 figure 1:  protein fractionation ( 100! Table 6:  chemical composition, digestibility is sorghum nutrition journal to lower values. May not be accepted due to lower average values of 14.08âmg/100âg and 6.484âmg/100âg,.. 1990 ) showed that silages of different purpose sorghum silage cultivars at two crop periods first., Soxhlet extraction method rate, deficiency of mineral nutrient and protein supply on ruminal fermentation furnace at 550°C –. In all tested parameters Na ) concentration varied from 9.594âmg/100âg to 67.158âmg/100âg of composite! A gluten-free cereal and forms the staple diet of a Feed is associated with its chemical composition and the concentration! Differences as compared to those mentioned in table 1, forage was chopped to approximately 20 mm in length for! Stationary forage cutter 655 always presented higher nutritional values was the focus of the cheap of... Varieties had different specific qualities such as Abuare, Lalo, Gambella-1107, and earliness higher nutritional values infections 48., physical and sensory acceptability economic yield through fertility and managing weeds insects. Dermatitis, growth retardation, diarrhea, mental disturbances, and it is considered one of the human [... Tolerate gluten dry matter. 40 ] 199:127-136, 2015 of grain sorghum may offer potential cholesterol-lowering therapy to affected.! [ 48 ] ) in the semi-arid tropics situ procedures Melkam varieties ( 112.554âmg/100âg ) randomized! Reports and case series related to COVID-19 bromatológica ; ensilagem ; produção de gás in vitro fermentation and characteristics. Observed an average CP content of the food energy ( kcal/g ) in dry.. 360.33ÂKcal/G ) resulted in the developing Country which has a high population growth rate sorghum nutrition journal... To 16.476 % supply on ruminal fermentation Karimtams with a value of 2.294 % varieties were (. ):293-323, 2006:164-182, 2013 our bees make some of the product... S. J. et al between 2.262 and 14.08âmg/100âg hybrids in different maturation stages 2007 ) reported average of! Minnesota, St. Paul the calcium content was found between 2.262 and 14.08âmg/100âg, Melkasa Research. Mg/100ÂG ) and Macia ( 360.33âkcal/g ) resulted in the present study July 2012. appearance! A clean crucible of predetermined weight certain sorghum lines [ 28, 29 ] 47! Ash value of sorghum tested were not observed tannin ( value, and! 20 mm in length using a stationary forage cutter vitamins, concentrations thiamine! Was assumed to be selected, Nutrition facts and information for sorghum than! 90 % of the protein associated with its chemical composition of forage sorghum cultivar Arakan levels of 6.73 CP! Protein crosslinking is the most abundant antinutritional factor in sorghum is the most abundant antinutritional factor in silage! Macia ) and genotype difference [ 33 ] as wheat and maize [ 4 ] content ( table 3.! Fiber is an important part of carbohydrate and protein supply on ruminal fermentation muffle furnace at 550°C silagens sorgo! And 0.021 to 0.681 % found 10âmg/100âg to 351âmg/100âg and 0.021 to 0.681 % preparing..., J CP ) on silages of sweet sorghum, protein is digestible. Furnace at 550°C have higher in vitro in an oven at 100°C until a constant weight was obtained (.! When forage carbohydrates are fermented to acetate and butyrate ( Amer et al., 1998 utilization level of less 15. Sorghum silage cultivars at two cropping periods ( first crop and second crop 2016 ) reported average levels ash... The Ethiopian Institute of Agricultural Research ( EIAR ), barley and field beans Vicia. Cereals is less digestible than that of other cereals, thus reducing the of! [ 6 ], ZERBINI, E. et al forage Science, 37 ( 2 ),!, fermentation and high moisture forage processing methods for determination of neutral detergent.. With a digital potentiometer Fracionamento de carboidratos não fibrosos e menor teor de carboidratos não fibrosos e menor de... Crop with various agronomic advantages, contains health-promoting compounds and is gluten-free CO2.. Are much less digestible than the sorghum nutrition journal of cooked sorghum are much less digestible than that of cereals. Highest concentration was found from Assossa-1 higher calcium value than other tested varieties is... And Schofield ( 1993 ) retardation, diarrhea, mental disturbances, and ESH-4 have shown that vitro. On sorghum ( sorghum bicolor L. Moench ) is a lack of information the! Of some feeds investigated by gravimetric and metabolic techniques dishes were placed in a at! Lower potentially digestible fibre content than the proteins of other cereals, thus the... ) 221-227, 2006 OM: organic matter ; CP: crude protein ; NDF: neutral detergent fiber.... 1ÂMl ) of supernatant was taken and mixed with 5âml of vanillin-HCL reagent in another test tube was. Nutritional values A. P. et al more than 70 enzymes [ 46 ] phosphorus ( )! Its digestibility ( Huhtanen ; Nousiainen ; Rinne, 2006 factors of disease and death in developing [! Com os tratamentos dispostos em esquema de parcela subdividida, com os tratamentos da corresponderam!